丧失 (sàng shī): to lose

That car accident caused him to lose both legs, but he didn't give up and later became a para-athlete.

Due to poor management, the company lost most of its market share and eventually had to declare bankruptcy.

Staying up late for a long time can make people lose the ability to concentrate, so you should get some rest earlier.

Facing enormous pressure, he lost confidence for a while, but with his family's encouragement, he pulled himself together again.