毁灭 (huǐ miè): to perish; to ruin; to destroy

The intense wildfire destroyed the entire forest within a few hours.

The earthquake and tsunami nearly destroyed this coastal city, and reconstruction work lasted for many years.

Scientists warn that a nuclear war could destroy human civilization.

He was addicted to gambling and ultimately destroyed his own future and family.

Overexploiting natural resources will destroy the ecological balance, leading to irreversible consequences.